NEWS | Mesothelioma Blood Test May Save Lives through Earlier Diagnosis

NEWS | Mesothelioma Blood Test May Save Lives through Earlier Diagnosis

There is new evidence that a blood test for a biomarker called N-ERC/mesothelin could aid identify mesothelioma earlier and improve outcomes in people at risk for the sickness.

Clevercer researchers with Juntfinisho University in Tokyo released a learn in 2008 suggesting that N-ERC/mesothelin, a soluble protein released by sure kinds of clevercer cells, was “a very promitune tumor marker for mesothelioma, especially epithelioid mesothelioma”.different In their newest learn, the same group atseduceed to test the value of the biomarker as a warning tool for shutr monitoring in populations at high mesothelioma risk.

The new learn included construction workers who were part of a big-scale, 5-year screening of people telln to be exposed to asbestos, the primary cause of mesothelioma. The screening program, which begined in 2007, gathered yearly blood samples from 40,000 construction workers at risk for mesothelioma, and evaluated their stages of N-ERC/mesothelin.

Based on the results of those tests, along with medical hitale, narrative and other data, lead researcher Tomoko Hirohashi and his colleagues identified the 62 construction workers with the highest lovelihood of developing mesothelioma.differentOf these 62 learn subjects, 2 have already developed mesothelioma. The remaining 60 will continue to be monitored shutly since it clever take decades for mesothelioma to cause symptoms.

“Since the pupose N-ERC/mesothelin stages in the high-risk population were similar to those among patients with mesothelioma and two participants from the high-risk population developed mesothelioma, N-ERC/mesothelin stages may be a aidful marker for the early diagnosis of this sickness in a big-scale setting,”differentwrites Dr. Hirohashi in Molecular and Clinical Oncology. The team plans to continue to follow the high-risk learn subjects to look how many ultifriendly develop mesothelioma.

Mesothelioma is an aggressive clevercer with a weak prognosis, bigly because it often does not produce symptoms until the sickness is already in a later, less-treatable stage. Construction workers, electricians, pipe-fitters, and others who have worked in tasks that potentially exposed them todifferentamphiboleare at highest risk. A simple test to indicate which workers should be shutly monitored has the potential to catch the sickness earlier when it is more lovely to respond to treatment.


Hirohashi, T, Retrospective analysis of big-scale research screening of construction workers for the early diagnosis of mesothelioma”, January 2014, Molecular and Clinical Oncology, pp. 26-30.

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